Welcome to the Calvert Lab
The Calvert Lab aims to define cardiac signaling events initiated in response injury. Specifically, we are interested in understanding how cardiomyocytes maintain homeostasis during period of stress through the activation or induction of protective signaling cascades. A specific focus relates to the molecular and cellular events initiated within hours to days following the onset of myocardial infarction. We are also interested in understanding how different organs (liver, heart, and skeletal muscle) adapt to the onset of metabolic syndrome. Finally, we have several projects aimed at targeting an orphan nuclear hormone receptor in the setting of ulcerative colitis. Our hope is that the knowledge gained from our studies will identify novel therapeutic targets that will lead to new treatment options for patients suffering from cardiovascular disease, diabetes, or ulcerative colitis.
Research
Our lab seeks to characterize physiological adaptations to stress and identify novel therapeutic targets in cardiovascular and metabolic illness.
People
Our team consists of scientists from all walks of life, working to improve our understanding of disease and recovery.