Principal Investigator
Dr. Jianhua Xiong joined Emory University School of Medicine as an Assistant Professor in 2024, bringing a wealth of experience and a strong research background. Dr. Xiong's laboratory focuses on investigating the metabolic regulation of cell fate and function, with a particular emphasis on prostate cancer. His research has yielded four senior-author papers published in reputable journals such as Molecular Biology of the Cell and G3: Genes, Genomes, Genetics.
Dr. Xiong's multidisciplinary approach incorporates cell biology, molecular biology, biochemistry, super-resolution imaging, transcriptomics, proteomics, metabolomics, histology, and the use of genetic and surgical mouse models.
Research
The Xiong Lab at Emory University investigates how metabolism, genetics, epigenetics, and post-translational regulation influence cell fate and function in urological health and disease, with an emphasis on prostate cancer initiation, progression, and resistance. We examine how metabolic signals and nutrient availability shape gene expression and cellular behavior in cancer, immune, and endothelial cells.
Using a multidisciplinary approach that integrates cell and molecular biology, biochemistry, multi-omics, advanced imaging, mouse models, and human tissue analysis, we aim to uncover key mechanisms driving tumor development, therapeutic resistance, and the tumor microenvironment.
Publications
Dr. Xiong's work has been listed in publications such as Molecular Cell, Trends in Biochemical Sciences, and Trends in Endocrinology & Metabolism.
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