Liikanen I, Lauhan C, Quon S, Omilusik K, Phan AT, Bartrolí LB, Ferry A, Goulding J, Chen J, Scott-Browne JP, Yustein JT, Scharping NE, Witherden DA, Goldrath AW. Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells. J Clin Invest. 2021 Apr 1;131(7):e143729. doi: 10.1172/JCI143729. PMID: 33792560; PMCID: PMC8011896.
Nakahata K, Simons B, Pozzo E, Shuck R, Kurenbekova L, Patel T, Yustein JT. MyoD-Cre driven alterations in mutant Kras and p53 leads to a mouse model with histological and molecular characteristics of human rhabdomyosarcoma with pre-clinical applications. Dis Model Mech. 2022 Feb 1.15(2):dmm049004. doi: 10.1242/dmm.049004. Epub 2022 Feb 17.PMID: 35174853 Editor’s Choice; Highlighted in special Ras Issue due out in 02/2022.
Tu J, Huo Z, Yu Y, Zhu D, Xu A, Huang MF, Hu R, Wang R, Gingold JA, Chen YH, Tsai KL, Forcioli-Conti NR, Huang SXL, Webb TR, Su J, Bazer DA, Jia P, Yustein JT, Wang LL, Hung MC, Zhao Z, Huff CD, Shen J, Zhao R, Lee DF. Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies. Proc Natl Acad Sci U S A. 2022 Apr 19;119(16):e2117857119. doi: 10.1073/pnas.2117857119. Epub 2022 Apr 11. PMID: 35412907; PMCID: PMC9169787.
Guo A, Huang H, Zhu Z, Chen MJ, Shi H, Yuan S, Sharma P, Connelly JP, Liedmann S, Dhungana Y, Li Z, Haydar D, Yang M, Beere H, Yustein JT, DeRenzo C, Pruett-Miller SM, Crawford JC, Krenciute G, Roberts CWM, Chi H, Green DR. cBAF complex components and MYC cooperate early in CD8+ T cell fate. Nature. 2022 Jul;607(7917):135-141. doi: 10.1038/s41586-022-04849-0. Epub 2022 Jun 22. PMID: 35732731; PMCID: PMC9623036.
Tsang SV, Rainusso N, Liu M, Nomura M, Patel TD, Nakahata K, Kim HR, Huang S, Rajapakshe K, Coarfa C, Man TK, Rao PH, Yustein JT. LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination. Oncogene. 2022 Dec;41(50):5373-5384. doi: 10.1038/s41388-022-02538-w. Epub 2022 Nov 8. PMID: 36348010.
Subasinghe SAAS, Ortiz CJ, Romero J, Ward CL, Sertage AG, Kurenbekova L, Yustein JT, Pautler RG, Allen MJ. Toward quantification of hypoxia using fluorinated EuII/III-containing ratiometric probes. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2220891120. doi: 10.1073/pnas.2220891120. Epub 2023 Apr 5. PMID: 37018203; PMCID: PMC10104500.
Nirala BK, Patel TD, Kurenbekova L, Shuck R, Dasgupta A, Rainusso N, Coarfa C, Yustein JT. MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma. JCI Insight. 2023 Jul 10;8(13):e164947. doi: 10.1172/jci.insight.164947. PMID: 37279073; PMCID: PMC10371352.