Qu Laboratory

Exploration of cell signaling, metabolic, and biomechanical control in both normal and malignant hematopoietic cell development is a primary focus in our research laboratory. Our specific emphasis lies in investigating the role of protein and lipid phosphatases within normal hematopoietic stem cells and leukemic stem cells. Through the examination of these phosphatases, our goal is to uncover the molecular mechanisms crucial for normal hematopoiesis and understand how their aberrant regulation is linked to hematological malignancies. Furthermore, the insights gained from these studies contribute to the development of innovative strategies and therapeutics, aiming to enhance stem cell-based therapy and improve the treatment of related leukemias.