About me
![Alawieh headshot](../../../../../images/a-l/brain_health/alawieh_ali_new_web.jpg)
Year
- PGY-6
Hometown
- Beirut, Lebanon
Areas of Interest
- Vascular Neurosurgery
Future Plans
- Academics
Awards/Honors
- Distinguished Graduate Student of the Year, Medical University of South Carolina, 2019
- Alpha-Omega-Alpha Honorary Society, 2018
- International Stroke Conference Junior Investigator Travel Award, American Heart Association, 2017
- Medical University of South Carolina Annual Research Day First Place Oral Presentation Awards 2015, 2016, 2017, and 2018
- Charleston Research Institute Best Presentation Award 2017 and 2018
- American Society for Clinical Investigation Travel Award, 2017
- CSCTR Junior Investigator Travel Award, 2017
- Outstanding Young Arab Neuroscientist Award, Society for Arab Neuroscientists, 2017
- Outstanding Research in Experimental Pathology Award, American Society of Investigative Pathology, 2016
- American Association of Immunology Young Investigator Award, 2016
- Raymond S. Greenberg Presidential Scholar, Medical University of South Carolina, 2015
Grants
Ongoing:
- VA Merit Award BX004256-01A1, “Role of Complement in Traumatic Brain Injury”, Alawieh (co-I), $300,000/year, 2018-2021
- VA Merit Award I01 RX001141-05A1, “Impact of Comorbidities on Stroke Outcomes and Treatments”, Alawieh (co-I), $275,000/year, 2018-2021
Completed:
- AHA Predoctoral Fellowship Award, “Targeting Complement Activation in Stroke” Alawieh (PI), $50,000/year, 2015-2017
- NIH/NIGMS U54GM10494-04, “Preclinical Characterization of Combined Post-Stroke Interventions with Rehabilitation”, Alawieh (Subaward co-I), $50,000/year, 2015-2017
- Farouk Jabre Award for Biomedical Research, Alawieh (co-I), $50,000, 2015
Memberships
- Alpha Omega Alpha Medical Honor Society
- American Association of Neurological Surgery
- American Heart Association/American Stroke Association
- American Physician Scientist Association
- Congress of Neurological Surgeons
- International Complement Society
- Society for Neurosciences
Hobbies
- Metaphysics
- Hiking
- Soccer
Education
- BS, American University of Beirut, 2013
- MD, Medical University of South Carolina, 2019
Publications
- Alawieh A, Kellogg RT, Chatterjee AR, Korson C, Lajthia O, Anadani M, Lena J, Spiotta AM. "Technical and clinical outcomes following thrombectomy for the various segments of the MCA". World Neurosurgery. 2019 Apr 28. PubMed PMID: 31042600.
- Anadani M, Spiotta A, Alawieh A, …, Gory B; TITAN (Thrombectomy In TANdem Lesions) Investigators. "Effect of extracranial lesion severity on outcome of endovascular thrombectomy in patients with anterior circulation tandem occlusion: analysis of the TITAN registry". Journal of Neurointerventional Surgery. 2019 Mar 6. PubMed PMID: 30842304.
- Alawieh A, Vargas J, Fargen KM, Langley EF, Starke RM, De Leacy R, Chatterjee R, Rai A, Dumont T, Kan P, McCarthy D, Nascimento FA, Singh J, Vilella L, Turk A, Spiotta AM. "Impact of Procedure Time on Outcomes of Thrombectomy for Stroke". Journal of the American College of Cardiology (JACC). 2019 Mar 5;73(8):879-890. doi: 10.1016/j.jacc.2018.11.052. PubMed PMID: 30819354.
- Alawieh A, Zaraket F, Alawieh MB, Chatterjee AR, Spiotta A. "Using machine learning to optimize selection of elderly patients for endovascular thrombectomy". Journal of Neurointerventional Surgery. 2019 Feb 2. pii: neurintsurg-2018-014381. doi: 10.1136/neurintsurg-2018-014381. PubMed PMID: 30712013.
- Anadani M, Orabi Y, Alawieh A, Chatterjee A, Lena J, Al Kasab S, Spiotta AM. "Blood pressure and outcome post mechanical thrombectomy". J Clin Neurosci. 2019 Apr;62:94-99. doi: 10.1016/j.jocn.2018.12.011. Epub 2018 Dec 26. PubMed PMID: 30594447.
- Anadani M, Alawieh A, Vargas J, Chatterjee AR, Turk A, Spiotta A. "First attempt recanalization with ADAPT: rate, predictors, and outcome". Journal of Neurointerventional Surgery. 2018 Dec 7. pii: neurintsurg-2018-014294. doi: 10.1136/neurintsurg-2018-014294. PubMed PMID: 30530772.
- Anadani M, Ajinkya S, Alawieh A, Vargas J, Chatterjee A, Turk A, Spiotta AM. "Intra-Arterial Tissue Plasminogen Activator Is a Safe Rescue Therapy with Mechanical Thrombectomy". World Neurosurgery. 2019 Mar;123:e604-e608. doi: 10.1016/j.wneu.2018.11.232. Epub 2018 Dec 7. PubMed PMID: 30529522.
- Alawieh A, Chatterjee AR, Vargas J, Chaudry MI, Lena J, Turner R, Turk A, Spiotta A. "Lessons Learned Over More than 500 Stroke Thrombectomies Using ADAPT With Increasing Aspiration Catheter Size". Neurosurgery. 2018 Nov 10. doi: 10.1093/neuros/nyy444. PubMed PMID: 30418596.
- Alawieh A, Starke RM, Chatterjee AR, Turk A, De Leacy R, Rai AT, Fargen K, Kan P, Singh J, Vilella L, Nascimento FA, Dumont TM, McCarthy D, Spiotta AM. Outcomes of endovascular thrombectomy in the elderly: a 'real-world' multicenter Journal of Neurointerventional Surgery. 2018 Nov 2. doi: 10.1136/neurintsurg-2018-014289. PubMed PMID: 30389899.
- Alawieh A, Langley F, and Tomlinson S. "Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice". Science Translational Medicine 2018 May 16;10(441):eaao6459. PMID: 29769288. (Featured cover story in the issue of May 16, 2018; also featured in Science, Scientific American, Nature Reviews Drug Discovery, FierceBiotech, and LaPresse).
- Alawieh A, Andersen M, Adkins DL, and Tomlinson S. "Acute Complement inhibition potentiates neurorehabilitation and enhances tPA-mediated neuroprotection". Journal of Neuroscience (2018): 0111-18. PMID: 29921716. PMCID: PMC6052238.
- Zheng H, Zhang B, Chhatbar PY, Dong Y, Alawieh A, Lowe F, Hu X, Feng W. Mesenchymal Stem Cell Therapy in Stroke: A Systematic Review of Literature in Pre-Clinical and Clinical Research. Cell Transplant. 2018 Dec;27(12):1723-1730. PubMed PMID: 30343609.
- Alawieh A, Chatterjee A, Feng W, Porto G, Vargas J, Kellogg R, Turk AS, Turner RD, Imran Chaudry M, Spiotta AM. Thrombectomy for acute ischemic stroke in the elderly: a 'real world' experience. J Neurointerv Surg. 2018 Dec;10(12):1209-1217. PubMed PMID: 29666180.
- Alawieh A, Langley F, Weber S, Adkins DL, and Tomlinson S. "Identifying the role of complement in triggering neuroinflammation after traumatic brain injury". Journal of Neuroscience (2018) 2197-17. PMID: 29437855. PMCID: PMC5858594.
- Alawieh A, Chaudry I, Turner RD, Turk A, Spiotta AM. "Infectious Intracranial Aneurysms: A Systematic Review of Epidemiology, Management and Outcomes". Journal of Neurointerventional Surgery (2018):neurintsurg-2017-013603. PMID: 29463620.
- Alawieh A, Zhao J, and Feng W. "Factors affecting post-stroke motor recovery: Implications on neurotherapy after brain injury". Behavioral Brain Research (2017) 15;340:94-101. PMID: 27531500. PMCID: PMC5305670.
- Alawieh A, Vargas J, Turner RD, Turk A, Chaudry I, Lena J, and Spiotta AM. "Equivalent favorable outcomes possible after thrombectomy for posterior circulation large vessel occlusion compared with the anterior circulation: the MUSC experience". Journal of Neurointerventional Surgery (2017):neurintsurg-2017-013420. PMID: 29222394.
- Alawieh A, Pierce A, Vargas J, Turk A, Turner RD, Chaudry I, and Spiotta AM. "The golden 35 min of stroke intervention with ADAPT: effect of thrombectomy procedural time in acute ischemic stroke on outcome". Journal of Neurointerventional Surgery (2017) PMID: 28465405. (Featured as Editor's Choice publication).
- Marshall K, Jin J, Atkinson C, Alawieh A, Qiao F, Lei B, Chavin KD, He S, and Tomlinson S. "Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice". Hepatology (2017). PMID: 28880403. PMCID: PMC5842100.
- Alawieh A, Sabra Z, Langley F, Bizri A, Hamadeh R, and Zaraket F. "Assessing the impact of the Lebanese National Polio Immunization Campaign using a population-based computational model". BMC Public Health1 (2017): 902. PMID: 29178859. PMCID: PMC5702188.
- Alawieh A, Tomlinson S, Adkins DL, Kautz S, and Feng W. "Preclinical and Clinical Evidence on Ipsilateral Corticospinal Projections: Implication for Motor Recovery". Translational Stroke Research (2017) 7:22-28. PMID: 28691140. PMCID: PMC5802360.
- Alawieh A and Tomlinson S. "Injury site-specific targeting of complement inhibitors for treating stroke". Immunological Reviews (2016) 274(1):270-280. PMID: 27782326. PMCID: PMC5098802.
- Alawieh A, Wang W, Narang A, and Tomlinson S. "Thromboembolic Model of Cerebral Ischemia and Reperfusion in Mice." Methods in Molecular Biology (2016) 1462:357-72. PMID: 27604728.
- Ren C, Kobeissy F, Alawieh A, Li N, Li N, Zibara K, Zoltewicz S, Guingab-Cagmat J, Larner SF, Ding Y, Hayes RL. "Assessment of serum UCH-L1 and GFAP in acute stroke patients". Scientific Reports (2016):6. PMID: 27074724. PMCID: PMC4830936.
- Alawieh A, Elvington A, Zhu H, Yu J, Kindy MS, Atkinson C, and Tomlinson S. ""Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement". Journal of Neuroinflammation (2015) 12(1):247. PMID: 26714866. PMCID: PMC4696299.
- Alawieh A, Sabra Z, Bizri A, Davies C, White R, and Zaraket F. "A computational model to monitor and predict trends in bacterial resistance". Journal of Global Antimicrobial Resistance (2015) 3(3):174-183. PMID: 26640775. PMCID: PMC4666607.
- Alawieh A, Narang A, and Tomlinson S. "Oncotarget (2015) 6(26):21769-70. PMID: 26318041. PMCID: PMC4673111.
- Alawieh A, Sabra M, Sabra Z, Tomlinson S, and Zaraket F. "Molecular Architecture of Spinal Cord Injury Protein Interaction Network". PLoS One (2015) 10(8):0135024. PMID: 26241741. PMCID: PMC4524728.
- Alawieh A, Mondello S, Kobeissy F, Shibbani K, Bassim M. "Proteomics studies in inner ear disorders: pathophysiology and biomarkers". Expert Reviews Proteomics (2015) 12(2):185-196. PMID: 25795149.
- Alawieh A, Sabra Z, Sabra M, Tomlinson S, and Zaraket F. "A rich-club organization in brain ischemia protein interaction network". Scientific Reports (2015) 5:13513. PMID: 26310627. PMCID: PMC4550934.
- Alawieh A, Elvington A, and Tomlinson S. "Complement in the homeostatic and ischemic brain". Frontiers in Immunology (2015) 12(6):417. PMID: 26322048. PMCID: PMC4533015.
- Alawieh A, Nasser Eldine R, Youssef M, and Bizri A. "Challenges in the Treatment of Acute Fulminant Hepatitis B: Case Report and Literature Review". Lebanese Medical Journal (2015) 63(2):103. PMID: 26164980.
- Razafsha M, Khaku A, Azari H, Alawieh A, Behforuzi H, Fadlallah B, Kobeissy FH, Wang KK, Gold MS. "Biomarker identification in psychiatric disorders: from neuroscience to clinical practice". Journal of Psychiatric Practice (2015) 21(1):37-48. PMID: 25603450.
- Alawieh A, Musharrafieh U, Jaber A, Berry A, Ghosn N, Bizri A. "Revisiting leishmaniasis in the time of war: the Syrian conflict and the Lebanese outbreak". International Journal of Infectious Diseases (2014) 29:115-119. PMID: 25449245.
- Alawieh A, Zaraket F, Sabra Z, Mondello S, and Kobeissy F. Bioinformatic approach to understanding interacting pathways in neuropsychiatric disorders". Methods in Molecular Biology (2014) 1168:157-72. PMID: 24870135
- Bizri A, Alawieh A, Ghosn N, Berry A, Musharrafieh U. "Challenges facing human rabies control: the Lebanese experience". Epidemiology and Infection (2014) 142(7):1486-1494. PMID: 24067449.
- Kobeissy F, Gulbakan B, Alawieh A, Karam P, Zhang Z, Guingab-Cagmat JD, Mondello S, Tan W, Anagli J, Wang K. "Post-genomics nanotechnology is gaining momentum: nanoproteomics and applications in life sciences". Omics: a Journal of Integrative Biology (2014) 18 (2), 111-131. PMID: 24410486. PMCID: PMC3920829.
- Kobeissy F, Alawieh A, Mondello S, Boustany R, and Gold MS. "Biomarkers in psychiatry: how close are we?". Frontiers in Psychiatry (2013) 3:114. PMID: 23316174. PMCID: PMC3539768.
- Alawieh A, Zaraket F, Li JL, Nokkari A, Razafsha M, Fadlallah B, Boustany RM, and Kobeissy F. "Systems biology, bioinformatics, and biomarkers in neuropsychiatry". Frontiers in Neuroscience (2012) 6:187. PMID: 23269912. PMCID: PMC3529307.
Book Edited
- Kobeissy F, Alawieh A, Zaraket F, and Wang K (Eds.). "Leveraging Biomedical and Healthcare Data: Semantics, Analytics and Knowledge". Elsevier Academic Press: 2019. ISBN: 9780128095560.
Book Chapters
- Alawieh A, and Spiotta A. "Infectious Intracranial Aneurysms – Epidemiology, Pathophysiology and Management". In: Spiotta, Turk, Chaudry and Turner, editors. Management of Cerebrovascular Disorders 2019. Springer, Cham.
- Alawieh A, Sabra Z, and Zaraket FA. "Computational Modeling in Global Infectious Disease Epidemiology". In: Leveraging Biomedical and Healthcare Data 2019 (pp. 133-141). Academic Press.
- Sabra M and Alawieh A. "Semiautomatic Annotator for Medical NLP Applications: About the Tool". In: Leveraging Biomedical and Healthcare Data 2019 (pp. 143-150). Academic Press.
- Sabra M, Alawieh A, and Zaraket FA. "Intractome Curation and Analysis for Stroke and Spinal Cord Injury Using Semiautomatic Annotations". In: Leveraging Biomedical and Healthcare Data 2019 (pp. 151-166). Academic Press.
- Alawieh A, Langley F, and Tomlinson S. "The Inflammatory Response and Its Effect on Rehabilitation-Induced Repair Processes After Stroke". In: Lapchak and Zhang, editors. Cellular and Molecular Approaches to Regeneration and Repair 2018 (pp. 509-520). Springer, Cham.
- Alawieh A, Sabra Z, Zhang Z, Kobeissy F, and Wang K. "Neuroproteomics and Neurosystems Biology in the Quest of TBI Biomarker Discovery". In: Wang K, Zhang Z, Kobeissy F, editors. Biomarkers of CNS injury and Neurological Disorders: CRC Press; 2014.
View Dr. Alawieh's Google Scholar profile.